Problem
54 million Americans suffer from low bone mass (osteopenia and osteoporosis)
1 in 2 women and 1 in 4 men over 50 will suffer an osteoporosis-related fracture
$19 billion spent per year on the US on osteoporotic fractures
75% of patients discontinue medication use within 12 months due to side effects
The opportunity
a consistent, manageable treatment that prevents osteoporosis.
The solution
Gentle mechanical stimulation that mimics weight-bearing exercise, providing an effective non-drug intervention.
Leveraging NASA technology
The OsteoBoost device relies on safe, natural, and effective whole-body vibration technology; using vibrational energy to turn stem cells into bone using the same mechanisms as physical exercise. WBV was first developed by NASA to combat bone mass loss experienced by astronauts in zero gravity.
Features
Applies dynamic mechanical stimulation to the hips and spine where fractures are most common
Worn around the waist like a normal belt 3-5 times per week for 10-20 minute sessions
Easy to use and comfortable to wear
Digital-health enabled to provide usage reminders and track compliance
Research
A 17-patient study (abstract accepted by Orthopedic Research Society in 2018) showed that OsteoBoost induced an acute reduction in bone loss as measured by biomarker NTx (mean: 14%, p<0.001) on par with results for bisphosphonates and weight-bearing exercise.
The Team
Daniel Burnett
MD, MBA Duke, Mayo Clinic, UCSF
Experienced entrepreneur; Founder of 10 startups with >$225M in investments for these companies. Track-record of bringing companies from concept to successful commercial launch.
Michael Jaasma
PhD UC Berkeley
PhD in Orthopedics. Doctoral research on bone cell responses to mechanical stimulation; Former Manager at the FDA, Division of Orthopedic Devices. Over 10 years of medical device R&D experience.
Nikhil Viswanathan
BS Duke
Cross-disciplinary engineer with experience in product design, testing, and manufacturing.
Carin Lindquist
BA UC Santa Barbara
Manager of clinical operations with experience running over 10 clinical trials for several novel medical devices.
Thi Nguyen
MBS Keck Graduate Institute
Advisors
Shane Mangrum
MD
Physical Medicine and Rehabilitation (PM&R) physician at Polaris Spine in Atlanta, GA; Specialist in nonoperative spine and musculoskeletal care. Dr. Mangrum is also a co-inventor of the OsteoBoost technology.
Gabriel Griego
BA
Sales and marketing guru in physical therapy and sports medicine space.
Previously with PowerBar, Game Ready, and AlterG
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