About Your Bones and Osteoporosis

Bone is a living organ that is in a constant cycle of renewal and removal. During the aging process, bone replacement (growth) slows down while bone removal (resorption) accelerates. This is particularly true for women just before, during and after menopause.2

Osteoporosis is a progressive disease that occurs when new bone creation is unable to keep up with bone loss.3 This causes bones to become porous (hence the name “Osteoporosis” and brittle, increasing the risk of fractures. Typically asymptomatic or “silent,” the condition is often not detected until the occurrence of a fracture.

Osteoporosis can be caused by various factors. The most common cause is the lack of estrogen and testosterone hormones.4 Other factors include lack of dietary calcium and vitamin D, smoking, and certain medications and medical conditions such as diabetes.2 Low bone mass affects about half of Americans over 50, with the majority of them being women.

Diagnosis is achieved primarily through the use of a Bone Mineral Density (BMD) assessment, also known as a DEXA (or DXA) scan or a bone density scan.  A diagnosis of Osteoporosis is made if the T-Score is -2.5 or below or if the patient has suffered a fragility fracture.  Osteopenia is diagnosed if the T-Score is between -1.0 and -2.49.  Osteopenia often progresses to Osteoporosis over time.

Osteoporotic fractures typically occur in the hip, spine, or wrist. While not a direct cause of death, fractures in the hip and spine severely limit independence, and are associated with a mortality rate of 33% and 20% after one year for men and women, respectively.5

Conventional Treatment Options

Treatment for Osteopenia is typically lifestyle changes.  First-line treatment options for Osteoporosis include lifestyle changes and various pharmaceuticals, depending on the cause of bone loss. Lifestyle changes usually include diet changes to increase calcium and vitamin D intake, as well as undertaking weight-bearing and resistance exercises such as walking or jogging and weightlifting. Medical therapies include bisphosphonates to slow bone resorption, increase bone density hormone replacement therapy and anabolic therapies to help slow down bone loss and build bone.6 Possible treatments are best discussed with your physician.

Where Vibration Therapy Fits In

Based on NASA technology developed to prevent bone loss for astronauts in zero gravity, vibration therapy devices simulate the mechanical loading of your bones during exercise, which stimulates bone growth. Whole body vibration therapy has been shown in several clinical studies to effectively encourage bone growth and prevent bone loss in the the hips and spine.7,8

Vibration therapy at the doses tested in the listed studies is safe and does not interfere with any current prescription medications or other therapeutic approaches. This makes vibration therapy an excellent treatment option in the fight to prevent or slow bone loss.

Vibration therapy devices and Osteoboost.

With whole-body vibration machines, the user typically stands on a vibrating platform and the delivery is more generalized.9 Compact and wearable, Osteoboost™ targets therapeutic vibration to the hips and lower spine, two of the most common spots for osteoporotic fractures. Positioned on the lower back, Osteoboost delivers low-intensity vibration where you need it the most.

Clinically proven to decrease bone resorption activity.

In a clinical trial conducted at the University of Nebraska Medical Center, OsteoBoost’s targeted vibration therapy decreased bone loss activity (NTX)  by an average of 14% in just one treatment. This is consistent with the effects of traditional treatment options, validating Osteoboost as an effective drug-free alternative in the fight against age-related bone loss.  See abstract here.

Clinical Trial Details

In collaboration with Dr. Laura Bilek at the University of Nebraska Medical Center, Bone Health Technologies conducted a clinical trial of Osteoboost.

The double-blinded, sham-controlled study enrolled 126 postmenopausal women with low bone mass who were not on bone-active medications. The data presented are strong evidence that supports the efficacy of the Osteoboost in reducing the decline of bone strength and bone density. The primary outcome measurement was the change in vertebral strength, as measured by Biomechanical Computed Tomography using finite element analysis. Per Protocol (PP) – subjects (those who used the device a minimum of 3 times per week throughout the year) in the Active Treatment group lost, on average, 0.48% bone strength, while those in the Sham group lost 2.84%, with a relative difference of 2.36% (P=0.014)– an 82% reduction in the rate of bone strength loss. Additionally, CT measurement of vertebral bone density was conducted and showed a 1.68% relative benefit for those using the Osteoboost– an 85% reduction in loss of bone density (P=0.008) in the PP group. Zero serious adverse events were reported.  The poster presented at the conference is linked here. The abstract was published here.

In a prior study, Bone Health Technologies and UNMC enrolled 17 postmenopausal women to evaluate the effect of the 30-minute treatment session on NTX, a biomarker of bone removal, a process that contributes to lower bone density with age.  Change in NTX levels via blood draws was noted in sessions during which the device was not turned on (control), and another during which each participant experienced a 30-minute OsteoBoost session. In all 17 women, the OsteoBoost targeted vibration therapy produced a decrease in NTX compared to the control session, with an average decrease of 14%. This is consistent with NTX changes provided by traditional treatment options such as drug therapy and exercise. 


“Osteoboost is easy to use and it actually feels good on my back. I keep it in my kitchen and now it’s just a part of my morning routine. It’s like giving my bones an extra 30-minute workout every day – what’s not to love?”

Brandi A.

“Osteoboost is super easy – easy to wear, quieter than I thought it would be, and has an added bonus of relaxing my low back muscles. I’ve been using it every day and like that it’s helping my bone health.”

Gwen R.

“The beauty of the Osteoboost wearable technology is that it is easy to add to a daily routine, there is no downside, and it offers vast potential to build better bones.”

Dr. Shane Mangrum, Physical Medicine & Rehabilitation

Clinical References

1. Martyn-St James M, Carroll S. (2008). Meta-analysis of walking for preservation of bone mineral density in postmenopausal women. Bone, 43(3);2008;521-531. doi: 10.1016/j.bone.2008.05.012
2. Osteoporosis. (2019, June 19). Retrieved February 24, 2020.
3. Learn what osteoporosis is and what it’s caused by. (n.d.). Retrieved February 25, 2020.
4. Demontiero O, Vidal C, Duque G. (2011). Aging and bone loss: new insights for the clinician. Therapeutic Advances in Musculoskeletal Disease, 4(2), 61–76. doi: 10.1177/1759720×11430858.
5. Lisk R, Yeong K. (2014). Reducing mortality from hip fractures: a systematic quality improvement programme. BMJ Quality Improvement Reports, 3(1). doi: 10.1136/bmjquality.u205006.w2103.
6. Eastell R, Rosen CJ, Black DM, Cheung AM, Murad MH, Shoback D. (2019). Pharmacological management of osteoporosis in postmenopausal women: an endocrine society* clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 104(5), 1595–1622. doi: 10.1210/jc.2019-00221.
7. Slatkovska L, Alibhai SMH, Beyene J, Cheung AM. (2010). Effect of whole-body vibration on BMD: a systematic review and meta-analysis. Osteoporosis International, 21(12), 1969–1980. doi: 10.1007/s00198-010-1228-z.
8. Lebrun C. (2012). Effects of whole-body vibration training on different devices on bone mineral density. Yearbook of Sports Medicine, 2012, 419–420. doi: 10.1016/j.yspm.2012.03.042.
9. Gómez-Cabello A, Ara I, González-Agüero A, Casajús J, Vicente-Rodríguez G. (2012). Effects of training on bone mass in older adults. Sports Medicine, 42(4), 301–325. doi: 10.2165/11597670-000000000-00000.
10. Osteoboost Is Effective In Preserving Bone Strength And Density Of The Spine In Women With Low Bone Mass
Laura D Bilek, PT, PhD, Laura E Flores, BA, Nancy Waltman, PhD, APRN-NP, Lynn R Mack, MD, Kara Smith, BS, MS, Derek Hillstrom, BS, Meghan Griffin, BS, Laura Yecies, MBA, Michael Jaasma, PhD
Journal of the Endocrine Society, Volume 7, Issue Supplement_1, October-November 2023, bvad114.449,
Published: 05 October 2023

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